Ethan Hughes, PhD
     

 Postdoctoral fellow

 The Solomon H. Snyder Department of Neuroscience

   
   
Contact information
 
 
E-mail
 ehughes (at) jhmi.edu
 
Lab Phone
 (410) 955-6949
 
Fax
 (410) 955-6942
     
 
Mailing Address
 Department of Neuroscience
 
 Johns Hopkins School of Medicine
   
 725 North Wolfe Street, WBSB 1001
   
 Baltimore, MD 21205
     
 
Education
 
 
  • B.S.      George Washington University
 
  • Ph.D.   University of Pennsylvania
 
 
Selected publications
 
 

Hughes EG*, Peng X*, Gleichman AJ, Lai M, Zhou L, Tsou R, Parsons TD, Lynch DR, Dalmau J, Balice-Gordon RJ. (2010) Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis J Neurosci. 30(17):5866-75.

* equal contribution

   
 

Hughes EG, Elmariah SB, Balice-Gordon RJ. (2010) Astrocyte secreted proteins selectively increase hippocampal GABAergic axon length, branching, and synaptogenesis. Mol. Cell. Neurosci. 43(1):136-45.

   
 

Lancaster E, Lai M, Peng X, Hughes E, Constantinescu R, Raizer J, Friedman D, Skeen MB, Grisold W, Kimura A, Ohta K, Iizuka T, Guzman M, Graus F, Moss SJ, Balice-Gordon R, Dalmau J. (2010) Antibodies to the GABA(B) receptor in limbic encephalitis with seizures: case series and characterisation of the antigen. Lancet Neurol. 9(1):67-76.

   

Lai M*, Hughes EG*, Peng X*, Zhou L, Gleichman AJ, Shu H, Matà S, Kremens D, Vitaliani R, Geschwind MD, Bataller L, Kalb RG, Davis R, Graus F, Lynch DR, Balice-Gordon R, Dalmau J (2009) AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location. Annals of Neurology 65(4):424-34

* equal contribution

 
   

Keene SD, Greco TM, Parastatidis I, Lee SH, Hughes EG, Balice-Gordon RJ, Speicher DW, Ischiropoulos H (2009) Mass spectrometric and computational analysis of cytokine-induced alterations in the astrocyte secretome. Proteomics 9(3):768-82

   
   

Dalmau J, Gleichman AJ, Hughes EG, Rossi JE, Peng X, Lai M, Dessain SK, Rosenfeld MR, Balice-Gordon R, Lynch DR (2008) Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol. 7(12):1091-8

     
   

Kayser MS, McClelland AC, Hughes EG, Dalva MB. (2006) Intracellular and trans-synaptic regulation of glutamatergic synaptogenesis by EphB receptors. J Neurosci. 26(47):12152-64

   
   

Elmariah SB, Oh EJ, Hughes EG, Balice-Gordon RJ (2005) Astrocytes regulate inhibitory synapse formation via Trk-mediated modulation of postsynaptic GABAA receptors. J Neurosci. 25(14):3638-50