Ethan G. Hughes, PhD
     

 Postdoctoral fellow

 The Solomon H. Snyder Department of Neuroscience

   
   
Contact information
 
 
E-mail
 ehughes (at) jhmi (dot) edu
 
Lab Phone
 (410) 955-6949
 
Fax
 (410) 955-6942
     
 
Mailing Address
 Department of Neuroscience
 
 Johns Hopkins School of Medicine
   
 725 North Wolfe Street, WBSB 1001
   
 Baltimore, MD 21205
     
 
Education
 
 
  • B.S.      George Washington University
 
  • Ph.D.   University of Pennsylvania
 
 
Selected publications
 
 
Hughes EG & Bergles DE (2014) Hidden progenitors repalce microglia in the adult brain. Neuron 82(2): 253-255.
   
 
Hughes EG*, Kang SH*, Fukaya M* & Bergles DE (2013) Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain Nature Neuroscience 16(6): 668-676.
   
 

Hughes EG*, Peng X*, Gleichman AJ, Lai M, Zhou L, Tsou R, Parsons TD, Lynch DR, Dalmau J, Balice-Gordon RJ. (2010) Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis J Neurosci. 30(17):5866-75.

   
 

Hughes EG, Elmariah SB, Balice-Gordon RJ. (2010) Astrocyte secreted proteins selectively increase hippocampal GABAergic axon length, branching, and synaptogenesis. Mol. Cell. Neurosci. 43(1):136-45.

   
 

Lancaster E, Lai M, Peng X, Hughes E, Constantinescu R, Raizer J, Friedman D, Skeen MB, Grisold W, Kimura A, Ohta K, Iizuka T, Guzman M, Graus F, Moss SJ, Balice-Gordon R, Dalmau J. (2010) Antibodies to the GABA(B) receptor in limbic encephalitis with seizures: case series and characterisation of the antigen. Lancet Neurol. 9(1):67-76.

   

Lai M*, Hughes EG*, Peng X*, Zhou L, Gleichman AJ, Shu H, Matà S, Kremens D, Vitaliani R, Geschwind MD, Bataller L, Kalb RG, Davis R, Graus F, Lynch DR, Balice-Gordon R, Dalmau J (2009) AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location. Annals of Neurology 65(4):424-34.

 
   

Keene SD, Greco TM, Parastatidis I, Lee SH, Hughes EG, Balice-Gordon RJ, Speicher DW, Ischiropoulos H (2009) Mass spectrometric and computational analysis of cytokine-induced alterations in the astrocyte secretome. Proteomics 9(3):768-82.

   
   

Dalmau J, Gleichman AJ*, Hughes EG*, Rossi JE, Peng X, Lai M, Dessain SK, Rosenfeld MR, Balice-Gordon R, Lynch DR (2008) Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol. 7(12):1091-8.

     
   

Kayser MS, McClelland AC, Hughes EG, Dalva MB. (2006) Intracellular and trans-synaptic regulation of glutamatergic synaptogenesis by EphB receptors. J Neurosci. 26(47):12152-64.

   
   

Elmariah SB, Oh EJ, Hughes EG, Balice-Gordon RJ (2005) Astrocytes regulate inhibitory synapse formation via Trk-mediated modulation of postsynaptic GABAA receptors. J Neurosci. 25(14):3638-50.

     
     
   
* equal contribution