Clinical and Research Postdoctoral Fellow, Division of Neuroimmunology, Department of Neurology and The Solomon H. Snyder Department of Neuroscience

Research Interests

Multiple sclerosis pathology; Oligodendrocyte remyelination and nervous system repair


B.S.   University of Pennsylvania

M.D., Ph.D.    University of Pennsylvania



Selected Publications

Orthmann-Murphy, J.L., and Calabresi, P.A. (2017). Therapeutic Application of Monoclonal Antibodies in Multiple Sclerosis. Clin. Pharmacol. Ther. 101, 52–64.

Orthmann-Murphy, J.L., Salsano, E., Abrams, C.K., Bizzi, A., Uziel, G., Freidin, M.M., Lamantea, E., Zeviani, M., Scherer, S.S., and Pareyson, D. (2009). Hereditary spastic paraplegia is a novel phenotype for GJA12/GJC2 mutations. Brain 132, 426–438.

Orthmann-Murphy, J.L., Enriquez, A.D., Abrams, C.K., and Scherer, S.S. (2007). Loss-of-function GJA12/Connexin47 mutations cause Pelizaeus-Merzbacher-like disease. Mol. Cell. Neurosci. 34, 629–641.

Orthmann-Murphy, J.L., Freidin, M., Fischer, E., Scherer, S.S., and Abrams, C.K. (2007). Two distinct heterotypic channels mediate gap junction coupling between astrocyte and oligodendrocyte connexins. J. Neurosci. 27, 13949–13957.



Department of Neuroscience

Johns Hopkins University School of Medicine

725 N. Wolfe St., WBSB 1001

Baltimore, MD 21205

Phone: (410) 955-6949

Fax: (410) 955-6942