{"id":2387,"date":"2020-05-07T00:00:29","date_gmt":"2020-05-07T00:00:29","guid":{"rendered":"http:\/\/bergleslab.com\/?p=2387"},"modified":"2020-06-02T19:44:18","modified_gmt":"2020-06-02T19:44:18","slug":"neumann-2020","status":"publish","type":"post","link":"http:\/\/bergleslab.com\/index.php\/2020\/05\/07\/neumann-2020\/","title":{"rendered":"Problems and Pitfalls of Identifying Remyelination in Multiple Sclerosis"},"content":{"rendered":"<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1934590920301399?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\">Cell Stem Cell<\/a>. 2020 May 7;26(5):617-619.<\/p>\n<h5>Problems and Pitfalls of Identifying Remyelination in Multiple Sclerosis <\/h5>\n<p>Bjoern Neumann, Sarah Foerster, Chao Zhao, Benedetta Bodini, Daniel S Reich, <strong>Dwight E Bergles<\/strong>, Ragnhildur Th\u00f3ra K\u00e1rad\u00f3ttir, Catherine Lubetzki, Luke L Lairson, Bernard Zalc, Bruno Stankoff, Robin J M Franklin.<\/p>\n<p><strong>Abstract<\/strong><br \/>\nRegenerative medicines that promote remyelination in multiple sclerosis (MS) are making the transition from laboratory to clinical trials. While animal models provide the experimental flexibility to analyze mechanisms of remyelination, here we discuss the challenges in understanding where and how remyelination occurs in MS.<\/p>\n<p><a href=\"http:\/\/bergleslab.com\/wordpress\/wp-content\/uploads\/2020\/06\/Neumann-2020.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">PDF<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Regenerative medicines that promote remyelination in multiple sclerosis (MS) are making the transition from laboratory to clinical trials. While animal models provide the experimental flexibility to analyze mechanisms of remyelination, here we discuss the challenges in understanding where and how remyelination occurs in MS. <\/p>\n","protected":false},"author":1,"featured_media":2388,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33,79],"tags":[131,132],"class_list":["post-2387","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publications","category-review","tag-multiple-sclerosis","tag-remyelination"],"_links":{"self":[{"href":"http:\/\/bergleslab.com\/index.php\/wp-json\/wp\/v2\/posts\/2387","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/bergleslab.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/bergleslab.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/bergleslab.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/bergleslab.com\/index.php\/wp-json\/wp\/v2\/comments?post=2387"}],"version-history":[{"count":3,"href":"http:\/\/bergleslab.com\/index.php\/wp-json\/wp\/v2\/posts\/2387\/revisions"}],"predecessor-version":[{"id":2392,"href":"http:\/\/bergleslab.com\/index.php\/wp-json\/wp\/v2\/posts\/2387\/revisions\/2392"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/bergleslab.com\/index.php\/wp-json\/wp\/v2\/media\/2388"}],"wp:attachment":[{"href":"http:\/\/bergleslab.com\/index.php\/wp-json\/wp\/v2\/media?parent=2387"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/bergleslab.com\/index.php\/wp-json\/wp\/v2\/categories?post=2387"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/bergleslab.com\/index.php\/wp-json\/wp\/v2\/tags?post=2387"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}